Reply from Drs Welinder-Olsson, Dotevall and Larsson

Drs. Negoescu and Abraham reply.

Drs. Waljee and Chung reply.

Drs. Moon and Min reply.

Drs. Littlejohn and Guymer reply.

Reply from Lars Larsson, Nicola Cacciani and Barry Dworkin

We are grateful for the thoughtful comments regarding our publication in The Journal Physiology, as they provide us an opportunity to clarify several points regarding the effects of mechanical ventilation, per se, on diaphragm muscle structure and function. In their comments Schellekens and co-workers are surprised by the lack of a significant decrease in diaphragm muscle fibre cross-sectional ...